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Review | Open Access

Emerging Application of Graphene Quantum Dots in Photodynamic/Photothermal and Hyperthermia Therapies for Cancer Treatment

Rahul S. Tade1( )Mahesh P. More2
Department of Pharmaceutics, H.R. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra 425405, India
Department of Pharmaceutics, Dr. Rajendra Gode College of Pharmacy, Malkapur, Maharashtra 443101, India
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Abstract

This study explores the emerging multifunctional applications of graphene quantum dots (GQDs) in cancer treatment, specifically focusing on photodynamic/photothermal therapy (PDT/PTT) and hyperthermia therapy. GQDs are a nanoscale carbon-based material with remarkable optical and thermal properties that hold considerable promise for various biomedical applications, particularly in cancer therapy. The review also focuses on emphasizing the importance of continued research and development in GQD synthesis, functionalization, and delivery systems. With their unique properties and multifaceted nature, GQDs offer promising opportunities for advancing cancer therapeutics toward more effective and targeted treatments. We discuss current trends and discrimination of GQD-based PDT/PTT strategies, showcasing the diverse techniques and approaches employed to maximize their therapeutic benefits. Furthermore, we elaborate on the critical dilemmas in the discrimination of GQD-based PDT/PTT strategies in clinical settings. Advancements in GQD-based PDT/PTT have the potential to significantly improve treatment efficacies and reduce side effects in cancer therapy.

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Nano Biomedicine and Engineering
Pages 111-128

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Cite this article:
Tade RS, More MP. Emerging Application of Graphene Quantum Dots in Photodynamic/Photothermal and Hyperthermia Therapies for Cancer Treatment. Nano Biomedicine and Engineering, 2025, 17(1): 111-128. https://doi.org/10.26599/NBE.2024.9290083

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Received: 14 January 2023
Revised: 23 February 2024
Accepted: 11 April 2024
Published: 10 May 2024
© The Author(s) 2025.

This is an open-access article distributed under  the  terms  of  the  Creative  Commons  Attribution  4.0 International  License (CC BY) (http://creativecommons.org/licenses/by/4.0/), which  permits  unrestricted  use,  distribution,  and reproduction in any medium, provided the original author and source are credited.